Learn more about some of the side effects that Eliquis may cause. Its not known if Eliquis is safe to take during pregnancy or while breastfeeding. A lumbar puncture is a procedure where fluid is collected from your spinal cord. Canada residents can call a provincial poison control center. Because its not known if breastfeeding while taking Eliquis is safe, its currently not recommended. For more information, see the Side effects explained section above. If youre pregnant or breastfeeding, or planning for either, talk with your doctor about your treatment options. More severe drug rashes, such as erythroderma, may cause permanent changes to skin pigmentation after treatment. If the side effects seem life threatening or you think youre having a medical emergency, immediately call 911 or your local emergency number. So Eliquis is currently not recommended for use during pregnancy. This site may provide links or references to other websites not affiliated with Bristol Myers Squibb or Pfizer. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. To learn more about conditions that can affect the safety of Eliquis, see the Precautions for Eliquis section below. You are encouraged to report negative side effects of prescription drugs to the FDA. WebMD does not provide medical advice, diagnosis or treatment. This is also referred to as leukocytoclastic vasculitis (LCV). But alcohol can increase your risk of bleeding. All rights reserved. This offer is non-transferable, no substitutions are permissible, and offer cannot be combined with any other rebate/coupon, free trial, or similar, Bristol-Myers Squibb and Pfizer reserve the right to rescind, revoke, or amend. This will help them determine if Eliquis may be a safe treatment option for you. For people taking ELIQUIS (apixaban) for atrial fibrillation: Do not stop taking ELIQUIS without talking to the doctor who prescribed it for you. Clopidogrel is a widely used antiplatelet agent, particularly after coronary stent implantation. This drug may not be the right treatment for you if you have certain medical conditions or other factors that affect your health. Ask your doctor or pharmacist for more details. If youre concerned about weight gain while taking Eliquis, talk with your doctor. Consult your doctor before breast-feeding. For details, see the Side effect specifics section above. In clinical trials, some people taking Eliquis reported having blood in their urine, which could be a sign of bleeding in the kidneys. If your doctor confirms youve had a serious allergic reaction to Eliquis, they may have you switch to a different treatment. In this case, your doctor will advise when you should stop taking Eliquis and when you should start taking it again. Anticoagulant-induced skin necrosis is a serious reaction that requires immediate medical attention. (2015). Eliquis has a boxed warning for this side effect. Please try again later. This clot may press on your spinal cord, which could cause long lasting or even permanent paralysis. ELIQUIS may need to be stopped prior to surgery or a medical or dental procedure. Mild reactions usually clear up once you stop taking the drug. This site is intended for U.S. residents 18 years of age or older. Weight Loss for Health and Longevity, Science Reveals How Red Meat Harms the Heart, Flavored Vapes Still in Stores Despite Federal Ban, New COVID Antiviral Pills: What You Need to Know, Dr. Whyte's Book: Take Control of Your Cancer Risk, WebMD Loses Cherished Leader Kristy Hammam, Health News and Information, Delivered to Your Inbox, List Eliquis side effects by likelihood and severity. But kidney-related side effects were not commonly reported in studies of the drug. These include boxed warnings from the Food and Drug Administration (FDA). Bleeding disorders often occur when blood doesn't clot properly. Ask for specific instructions about stopping or starting this medication. Symptoms can be mild or serious and can include: For mild symptoms of an allergic reaction, call your doctor right away. Spinal and epidural injections are used to administer medication such as pain relievers or anesthesia into your spinal cord. To learn more about this, see Side effect specifics below. If any of these effects last or get worse, tell your doctor or pharmacist promptly. Eliquis works by reducing your bloods ability to form clots. Which one is right for you depends on a variety of different factors. In clinical trials, minor bleeding was the most common side effect reported with Eliquis. Ask your doctor or pharmacist about how much alcohol you may safely drink. Mild side effects that have been reported with Eliquis include: bruising. However, older adults may be more likely to have conditions that can raise the risk of side effects with Eliquis. What should I do if I become pregnant during Eliquis treatment? Before taking apixaban, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. ELIQUIS is available in 2.5-mg and 5-mg tablets. We avoid using tertiary references. Symptoms of serious bleeding may include: If you have symptoms of serious bleeding, call your doctor right away. risk of developing an epidural blood clot, To Reduce Stroke Risk Due to AFib Not Caused by, eligibility requirements and terms of use. Warfarin is a blood thinner that can be more effective when restricting foods that are vitamin K-rich. Theyll be able to recommend when to stop taking the drug. Our website services, content, and products are for informational purposes only. Learn more about the symptoms of poison oak rash and how to treat it here. Learn about risks, signs to contact a doctor, and more. In the early stages, DIC causes your blood to clot excessively. Look out for the following icons as you read: Do not stop taking ELIQUIS without talking to the doctor who prescribed it to you Drugs that may cause . To use Elise, please try going to this website on a phone, tablet, or another internet browser, such as Chrome, Firefox, or Safari. You may not notice symptoms of DRESS for 2 to 6 weeks after starting a new drug. You may have a higher risk of bleeding if you take ELIQUIS and take other medicines that increase your risk of bleeding, such as aspirin, nonsteroidal anti-inflammatory drugs (called NSAIDs), warfarin (COUMADIN), heparin, selective serotonin reuptake inhibitors (SSRIs) or serotonin norepinephrine reuptake inhibitors (SNRIs), and other medicines to help prevent or treat blood clots. There is no single AFib diet, but diets such as the Mediterranean diet may reduce symptoms, lower risk factors, and promote heart health. If you stop taking this medication early, you have a higher risk of forming a serious blood clot (such as a stroke, blood clot in the legs/lungs). Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease, kidney disease, bleeding problems (such as bleeding of the stomach/intestines, bleeding in the brain), blood disorders (such as anemia, hemophilia, thrombocytopenia), recent major injury/surgery, stroke, a certain clotting disorder (antiphospholipid syndrome), frequent falls/injuries. We link primary sources including studies, scientific references, and statistics within each article and also list them in the resources section at the bottom of our articles. Its not known if Eliquis can pass into breast milk. Before taking Eliquis, there are certain precautions to consider. An active ingredient is what makes a drug work. Healthline Media does not provide medical advice, diagnosis, or treatment. Depending on the severity of the reaction, drug rashes may not necessarily be a cause for worry. Analysis Eliquis Bleeding-into-the-skin Eliquis and Bleeding into the skin - a phase IV clinical study of FDA data Summary: Bleeding into the skin is found among people who take Eliquis, especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months. I developed a rash , red, itchy on my back after starting Eliquis. Talk with your doctor if youre concerned about kidney-related side effects with Eliquis. If you have to stop taking ELIQUIS, your doctor may prescribe another medicine to help prevent a blood clot from forming. If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. If youre concerned about side effects that you may have while taking a higher dosage of Eliquis, talk with your doctor or pharmacist. Because of the possible risk to the infant, breast-feeding while using this drug is not recommended. However, if you stop Eliquis sooner than your doctor recommends, you may have an increased risk of blood clots. Mild side effects can occur with Eliquis use. People taking this medication may bleed near the spinal cord after certain spinal procedures. Symptoms of blood clots in your spine include: Before having any spinal procedures done, tell your doctor that youre taking Eliquis. Eliquis reduces your bloods ability to form clots, and as a result, it can increase your risk of bleeding. Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. In rare cases, Eliquis may cause serious bleeding. Alcohol doesnt interact with Eliquis. [Text HELP to 69108 for help.] However, home remedies could help, like apple cider vinegar and tea tree oil. For people taking ELIQUIS (apixaban) for atrial fibrillation: Do not stop taking ELIQUIS without talking to the doctor who prescribed it for you. Taking a blood thinner as part of your AFib treatment can reduce your risk of blood clots and stroke. This is the most serious warning from the Food and Drug Administration (FDA). Liver problems. Since Eliquis can also cause bleeding, drinking alcohol while taking Eliquis may further increase your risk of bleeding. Side effects of Eliquis typically get better after you stop taking the medication. Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. What are the possible serious side effects of ELIQUIS? These are not all of the possible side effects of ELIQUIS. Learn about causes, diagnosis, and more. When leaving the hospital following hip or knee replacement, be sure that you will have ELIQUIS available to avoid missing any doses. At this time, theres not enough information to know whether Eliquis may cause harm to a developing fetus. They include: Hemorrhage: Serious bleeding in the gastrointestinal tract Serious bleeding in the brain (hemorrhagic stroke) Serious bleeding within the eye Anemia Nausea This is not a complete list of possible side effects. On the other side, there is a medication identification number. If you have a blood disorder called triple-positive APS, you may have a raised risk of blood clots with Eliquis. Eliquis may not be right for you if you have certain medical conditions. This can lead to blood clots forming, which can travel to other parts of your body (such as the lungs or legs) or increase your risk for stroke. If this side effect is severe or bothersome to you, your doctor may be able to recommend ways to help prevent it. They can determine the best treatment plan for you. All decisions regarding patient care mustbe made with a healthcare provider, considering the unique characteristics of the patient. A boxed warning is a serious warning from the Food and Drug Administration (FDA). While taking ELIQUIS, you may bruise more easily and it may take longer than usual for any bleeding to stop. Your risk of developing a spinal or epidural blood clot is higher if: If you take ELIQUIS and receive spinal anesthesia or have a spinal puncture, your doctor should watch you closely for symptoms of spinal or epidural blood clots or bleeding. People with triple-positive APS may have an increased risk of blood clots from Eliquis. A drug rash or other reaction may occur for several reasons, such as: In some cases, drug rashes can be idiopathic, meaning theres no known direct cause. Drug rashes can appear as a variety of skin rashes, including pink to red bumps, hives, blisters, red patches, pus-filled bumps (pustules), or sensitivity to sunlight. You are being redirected to a Bristol Myers Squibb corporate site. Last medically reviewed on July 21, 2022. Do not take ELIQUIS if you currently have certain types of abnormal bleeding or have had a serious allergic reaction to ELIQUIS. If you have any questions, ask your doctor or pharmacist. Get medical help right away if you have any of the following symptoms: Sudden chest pain or chest tightness Sudden swelling of your face or tongue Trouble breathing Wheezing unexpected bleeding or bleeding that lasts a long time, such as unusual bleeding from the gums, nosebleeds that happen often, or menstrual or vaginal bleeding that is heavier than normal, bleeding that is severe or you cannot control, red, pink, or brown urine; red or black stools (looks like tar), coughing up or vomiting blood or vomit that looks like coffee grounds. Triple-positive antiphospholipid syndrome (APS). Theyll recommend a different medication to take for treating or preventing blood clots. Bristol Myers Squibb and Pfizer are not responsible for the content of such other sites and shall not be liable for any damages or injury arising from users access to such sites. This data may be used, For help, text HELP to 69108 or contact your mobile carrier. If you have liver problems, Eliquis may build up in your body. Eliquis may cause mild side effects other than the ones listed above. If you have any bleeding thats severe or wont stop, call your doctor right away. Learn about causes and risk factors, plus what to do if it, A purpuric rash is made up of small, discolored spots under your skin from leaking blood vessels. If you get this reaction, it will usually happen soon after you take a dose of ELIQUIS. If you have a severe liver problem, your doctor will likely not prescribe Eliquis. Stopping ELIQUIS increases your risk of having a stroke. To our knowledge, there is only one other reported case due to apixaban in the literature [ 1 ]. ELIQUIS is available in two different tablets. AFib Not Caused by a Heart Valve Problem. Your skin may grow scaly within several days. All decisions regarding patient care must be made with a healthcare provider, considering the unique characteristics of the patient. Your doctor will recommend treating the bleeding before you start treatment with Eliquis. Like other drugs, Eliquis can cause mild to serious side effects, also called adverse effects. These include dentists, dental hygienists, and anyone administering vaccines or other injections. If you miss a dose of ELIQUIS, take it as soon as you remember, and do not take more than one dose at the same time. Before having surgery or any medical/dental procedures (especially spinal puncture or spinal/epidural anesthesia), tell your doctor or dentist that you are taking this medication and about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). You and your doctor should decide if you will take ELIQUIS or breastfeed. If you get this reaction, it will usually happen soon after you take a dose of ELIQUIS. If youve had an allergic reaction to Eliquis or any of its ingredients, your doctor will likely not prescribe Eliquis. Use this medication regularly to get the most benefit from it. Having certain medical conditions may increase the risk of side effects from taking Eliquis. Possible serious side effects include bleeding or a reaction to ELIQUIS itself. Drug rashes may involve the entire skin surface, or they may be limited to one or a few body parts. Most are minor and related to an increased risk of bleeding with this drug. Additional symptoms are severe and can involve the internal organs, such as: Possible drugs that can cause DRESS include: DRESS is a very serious reaction that requires immediate medical attention. Dosage of drugs is not considered in the study. Stopping Eliquis isnt known to cause withdrawal symptoms. If youre taking Eliquis and need an epidural injection for pain relief during labor, you may have an increased risk of developing a spinal blood clot. You may experience side effects during your treatment with Eliquis. Take ELIQUIS exactly as prescribed by your doctor. This is because ELIQUIS is a blood thinner medicine that reduces blood clotting. Eliquis may cause serious side effects. If you drink alcohol, talk with your doctor about how much is safe to consume while taking Eliquis. You may notice small, raised or flat lesions on reddened skin. Females who are able to become pregnant: talk with your healthcare provider about pregnancy planning, and your risk of severe uterine bleeding if you are treated with blood thinner medicines, including ELIQUIS. In studies, the majority of people taking Eliquis were ages 65 years and older. If you get this reaction, it will usually happen soon after you take a dose of ELIQUIS. * If you have a stroke after stopping Eliquis, this could lead to long-term problems. Is exercise more effective than medication for depression and anxiety? This could lead to weight gain. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. Boxed warnings are the most serious warnings from the Food and Drug Administration (FDA). The rest of the body was spared, and the remainder of examination was unremarkable. But in studies, nosebleeds were not a commonly reported side effect in people taking Eliquis. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. These include severe urticaria, erythroderma, SJS/TEN, anticoagulant-induced skin necrosis, and DRESS. For example, you may have internal bleeding in your digestive system, lungs, brain, liver, kidneys, abdominal cavity, joints, or eyes. Its not known whether its safe for people with an artificial heart valve to take Eliquis. LCV is a histopathologic diagnosis given to a small-vessel vasculitis where immune complexes deposit in the vessel walls. At first, you might notice your skin turns red and painful. This causes swelling in the form of a hematoma. You should always consult your doctor or another healthcare professional before taking any medication. Get medical help right away if you have sudden chest pain or chest tightness, have sudden swelling of your face or tongue, have trouble breathing, wheezing, or feeling dizzy or faint. Tell your doctor about all of the medicines you take, including any over-the-counter medicines, vitamins, and herbal supplements. This medication is a blood thinner and increases your risk of bleeding. Refill your prescription before you run out. They alert doctors and patients about drug effects that may be dangerous. Side effects arent common with Eliquis. Do not stop taking this medication without consulting your doctor. Learn more here. What is the latest research on the form of cancer Jimmy Carter has? Having certain spinal procedures during Eliquis treatment may increase the risk of blood clots in your spine. Drug rashes, or drug eruptions, are reactions your skin may develop in response to certain drugs. Poison oak rash can produce a severe, painful rash. However, these side effects werent reported in clinical trials of Eliquis. Bleeding in this area can cause paralysis that lasts a long time or could become permanent. Abstract. * Eliquis has a boxed warning for this side effect. Boxed warnings are the most serious warnings from the Food and Drug Administration (FDA). However, its possible you may gain weight due to the reason youre taking Eliquis. This could raise your risk of side effects, especially bleeding. You are a resident of the United States, Puerto Rico, or other select U.S. If you have an artificial heart valve, your doctor will likely not prescribe Eliquis. This medication can increase your risk of bleeding and may make active bleeding worse. Also, it can sometimes cause thrombocytopenia (low platelet count). Is my risk of side effects increased due to other medications that Im taking? In clinical trials, side effects of Eliquis in older adults were similar to those in younger adults. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. hopkinsmedicine.org/healthlibrary/conditions/dermatology/drug_rashes_85,P00280, ejinme.com/article/S0953-6205(15)00414-8/fulltext, aaaai.org/tools-for-the-public/conditions-library/allergies/medications-and-drug-allergic-reactions, fda.gov/drugs/resourcesforyou/specialfeatures/ucm464195.htm, How to Recognize and Get Help for Hypersensitivity Syndrome, Overview of Purpuric Rash, a Symptom of Some Conditions, Debra Sullivan, Ph.D., MSN, R.N., CNE, COI, How to Get Rid of Dark Circles Permanently, Debra Rose Wilson, Ph.D., MSN, R.N., IBCLC, AHN-BC, CHT. Only valid in the United States, Puerto Rico, and other select U.S. For People at Risk of Stroke due to AFib Not Caused by a Heart Valve Problem. Curious about drug rashes and what they look like? Liver problems. Hello. Tell your doctor right away if you have any of these signs or symptoms (especially in your legs and feet) when taking ELIQUIS: A reaction to ELIQUIS can cause hives, rash, itching, and possibly trouble breathing. One is about the risk of spinal blood clots with spinal procedures. To learn more, see Side effect specifics below. Talk to your healthcare team before any medical procedures. You should not do both. These are just a few of the more common side effects reported by people who took Eliquis in clinical trials: * For more information about this side effect, see Side effect specifics below. Stopping ELIQUIS increases your risk of having a stroke. ELIQUIS can cause bleeding, which can be serious, and rarely may lead to death. What does Eliquis look like? They can become very itchy. But its possible that taking Eliquis during pregnancy may increase the risk of bleeding. Warfarin is an anticoagulant medicine (blood thinner). Otherwise, call a poison control center right away. What are the possible serious side effects of ELIQUIS? How Viagra became a new 'tool' for young men, Ankylosing Spondylitis Pain: Fact or Fiction, Side effects of 2.5-mg vs. 5-mg strengths, nonsteroidal anti-inflammatory drugs (NSAIDs), selective serotonin reuptake inhibitors (SSRIs), serotonin-norepinephrine reuptake inhibitors (SNRIs), https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/202155s034lbl.pdf, Cardiovascular health: Insomnia linked to greater risk of heart attack. As such, the most common side effects of Eliquis include: Bleeding Bruising more easily than normal Anemia Other common side effects of Eliquis may include: Allergic reaction (skin rash, itching, flushing) Fatigue Nausea Headaches Dizziness Do not run out of ELIQUIS. Cellulitis occurs most often on the lower leg, but other parts of the body may be affected as well. For example, if the rash is very itchy, an antihistamine or oral steroid can help manage the itching until the rash clears up. Ask them what other medications may be better options for you. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. See below for more important safety information about ELIQUIS. The clots location and severity will determine the treatment. This may include bleeding in organs such as the kidneys. Be sure to tell them right away if you have any of the symptoms listed above. How do the side effects of Eliquis compare with side effects of other medications used for my condition. Can diet help improve depression symptoms? Treatment and home management for blood clots, How to tell if it is a bruise or a blood clot, Blood-thinning foods, drinks, and supplements, help prevent DVT and PE from occurring again after the initial clot has been treated, help prevent DVT and PE after hip or knee replacement surgery, Spinal blood clots with spinal procedures., Increased risk of blood clots if Eliquis treatment is stopped early., have had past spinal surgery or problems with your spine, have had difficult or repeated spinal procedures in the past, have an epidural catheter (thin tube placed into your spine to deliver medication), bleeding that takes longer than usual to stop, menstrual periods that are heavier than usual or last longer than usual, avoiding contact sports and other sports with a risk of injury, wearing gloves when using tools such as knives or scissors, swelling under your skin, typically in your eyelids, lips, hands, or feet, swelling of your mouth, tongue, or throat, which can make it hard to breathe. Another rare side effect of Eliquis is blood in the urine, which could be due to a kidney-related problem. What is ELIQUIS? However, some of these rashes may be accompanied by itching or tenderness. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088. What should I discuss with my healthcare team before starting ELIQUIS? Do not run out of ELIQUIS. In the meantime, your doctor may prescribe a different medication to help prevent blood clots. Eliquis can build up in your body if your liver isnt working properly. But its also possible to develop serious side effects from this medication. Erythroderma can become serious and life threatening. Spinal or epidural blood clots (hematoma). [For questions about the Program, call. Your doctor will monitor you for symptoms of spinal blood clots after the procedure. There are many possible triggers of these digestive problems. Examples of commonly reported side effects of Eliquis. Before starting Eliquis treatment, tell your doctor if you have triple-positive APS. See more about possible serious side effects. Eliquis hasnt been reported to cause other long-term side effects (side effects that last for a long time). Were sorryElise, our Virtual Assistant, is not available at this time. Territory. If you suspect you have a drug rash, talk with your doctor right away. Most of the drugs side effects are mild. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. Your doctor may direct you to take a different "blood thinning" or antiplatelet medication to reduce your risk. You can then share this information with your doctor. Boxed warnings are the most serious warnings from the FDA. ELIQUIS is a prescription medicine used to reduce the risk of forming a blood clot in the legs and lungs of people who have just had hip or knee replacement surgery. You should avoid drinking large amounts of alcohol while taking Eliquis. If you have a nosebleed, pinch the top of your nose tightly for 10 minutes to help stop the bleeding. If you have a spinal procedure while taking Eliquis, you may have a higher risk of spinal blood clots if you: Symptoms of a spinal blood clot may include: If you need to have a spinal procedure while taking Eliquis, make sure your doctor knows that youre taking this medication. Eliquis has a boxed warning for the risk of blood clots if stopping Eliquis treatment early. Do not stop taking it any earlier unless you have discussed it with your doctor first. Get answers to some frequently asked questions about the side effects of Eliquis. Do not store in the bathroom. I've been on Apixaban for a 2 or 3 of years and over the last year I've started to have skin problems. Bleeding that is severe oryou cannotcontrol, You have a history of difficult or repeated epidural or spinal punctures, currently have certaintypes of abnormalbleeding, You may have a higher risk of bleeding if you take. This website is best viewed using the horizontal display on your tablet device. If you need a spinal procedure while taking Eliquis and youre concerned about the risk of spinal blood clots, talk with your doctor. Get medical help right away if you have any signs of very serious bleeding, including: vision changes, confusion, trouble speaking, weakness on one side of the body. Bruising was a common side effect reported by people in studies of Eliquis. Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available.
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