A trial of children with ADHD found that Pycnogenol may improve attention, possibly by increasing the total antioxidant status and reducing DNA damage. As noted, aspirin can cause severe gastrointestinal issues. Pycnogenol (100 mg/day) given to 44 older healthy people with high oxidative stress improved cognitive function, attention, mental performance, and reduced oxidative stress after 12 months [21]. Theres evidence that Pycnogenol may be a promising nootropic for various groups of people, including middle-aged professionals, students, and people with mild cognitive decline like brain fog. From diabetes and sexual function to sports performance and beautiful skin, pine bark extract may be worth exploring to provide results youre looking to achieve. This review noted that pine bark extract may also help with: In addition to its skin-healing properties, pine bark extract also shows promise for helping children manage ADHD symptoms. Consequently, blood pressure is lowered. A trial of 53 students found that pycnogenol may improve cognitive function, memory, attention, mood, and mental performance after 8 weeks [20]. 5. This condition can be temporary or permanent however, some studies have indicated that pine bark extract may help alleviate these symptoms due to its high presence of antioxidants. WebMD does not provide medical advice, diagnosis or treatment. In one study, people with high blood pressure were examined to see how the supplement impacted their blood pressure. Clinical research suggests that Pycnogenol is possibly effective for improving athletic performance. Pycnogenol treatment lowered the ACE-inhibitor dose required to control blood pressure, and lowered fasting glucose levels as well. Learn about this tree-based pill and how it might be able to help you. The study showed that many people who participated had a drop in their systolic blood pressure after taking Pycnogenol. - Apply a hot compress to the anus or soaking it in a shallow tub of hot water several times a day. Pycnogenol is known under different names in some countries, such as Oligopin, and Flavangenol in Japan [4, 5]. In the study, the placebo group had higher IgE antibodies to the birch allergen than those who took Pycnogenol during the allergy season [17]. ( 1) 2. SelfDecode is a personalized health report service, Add to Cart. According to a large analysis, Pycnogenol may reduce osteoarthritis symptoms and pain short-term [45, 46]. Typical doses range from 50 milligrams to 450 milligrams per day. Pycnogenol may have benefits for heart and artery health. That way, your doctor can check on any potential side effects or interactions with medications. Research suggests that taking pycnogenol improves mental function and memory in both young adults and the elderly. (2017). The Best Supplements for Healthy Digestion, How to Get the Protective Power of Vitamin K. A combination supplement (pycnogenol with collagen, coenzyme Q10, and other ingredients) reduced skin aging, elasticity, hydration, and tonicity in a study of 30 women [65]. 10 Ways to Control Blood Sugar without Medication, Pycnogenol (French Maritime Pine Bark Extract): 12 Benefits According to Studies, Reduces leaky blood vessels by making the wall proteins (collagen, elastin) more resistant to damage, Helps maintain high vitamin C and E blood levels for their antioxidant effects, Inhibits platelet aggregation like low-dose aspirin, Reduces hardening in the arteries by increasing nitric oxide production in blood vessels, leading to greater dilatation, Counteracts the damaging effects of ultraviolet radiation, Stimulates the immune system by boosting T and B cell functions, Protects brain cells from toxic chemicals. (14, 15). Memorial Sloan-Kettering Cancer Center web site: "About Herbs: Pine Bark Extract. This can cause pain, especially in areas of the body that are used repeatedly, like your hands, fingers, and knees. Forty patients were treated with either 600 mg chestnut seed extract a day or 360 mg Pycnogenol a day over a period of four weeks. Also, its important to note that some of these studies were funded by Horphag Research, the original developers and exclusive marketers of Pycnogenol. For poor circulation: 45360 milligrams daily or 50100 milligrams three times daily. There havent been enough studies yet to change practice protocols for treating children. Perimenopausal women who took pine bark extract for eight weeks noticed decreased cholesterol and triglyceride levels. Organika Pycnogenol 50mg 100 Tablets. This condition can be temporary or permanent however, some studies have indicated that pine bark extract may help alleviate these symptoms due to its high presence of antioxidants. A study of 58 people with high blood pressure suggests that even lower doses (100 mg/day) may improve blood vessel health and reduce markers of high blood pressure (endothelin-1) after 12 weeks. For mild high blood pressure: 200 milligrams daily. These antioxidants scavenge those damaging free radicals in an effort to eliminate them, ultimately preventing disease. Pine bark extract has been studied with regard to its ability to help diabetic patients. Pycnogenol may stimulate the immune system. Pycnogenol significantly reduced the swelling as well as the feeling of heaviness. $109.99. In one study, 200 mg a day of Pycnogenol taken three hours prior to the first cigarette for the day for two months significantly reduced cigarette-induced platelet aggregation. Add to Cart. Pycnogenol has four main components that contribute to its benefits for men's health. American Cancer Society: "Pine Bark Extract.". It also reduced LDL cholesterol at a slightly lower dose (125 mg/day) in those with type 2 diabetes in a clinical trial of 48 people after 12 weeks. Mental function. In patients with chronic venous insufficiency, the number of muscle cramps decreased from 6.3 to 2.6; in athletes from 8.6 to 2.4. Some studies have suggested it may modestly improve blood pressure, cholesterol, and C-reactive protein. In the study, it reduced cold symptoms and complications, the number of lost working days, and the use of over-the-counter medications compared to those who did not supplement with the extract [60]. This key chemical, proanthocyanidin, is also found in high concentrations in apples, cranberries, coca, grapes, and red wine. Most have similar amounts of active substances and are often sold under the brand name Pycnogenol [6]. They were given Pycnogenolfor a period of 10 days. Helps maintain high vitamin C and E blood levels for their antioxidant effects. Animal studies have found that gotu kola makes it harder . This supplement may also increase muscle endurance and performance after a single pre-exercise dose according to a study of 9 cyclists [12, 13]. In one study, 10 patients were treated with placebo and 30 patients were treated with Pycnogenol (100 mg twice or three times daily for two months). L-arginine is more effective when paired with L-citrulline or pycnogenol to combat erectile dysfunction and improve exercise performance. Add to Cart. There is insufficient evidence to support the use of Pycnogenol for any of the uses listed below. Clearer skin, healthier hair there are a lot of claims about the health benefits of biotin. Make sure to seek out the advice of your physician prior to using pine bark extract or the branded name, Pycnogenol. Instead, use plain water to wipe yourself and then dry your bottom afterward. You can refer to the National Institutes of Healths dosage guidelines for specific conditions. Studies were conducted in Turkey on subjects who underwent abdominal surgery to determine if the pine bark extract could help reduce the inflammation. Grape seed extract may be more beneficial for those who are obese. Cigarette smoking increases platelet aggregation. Video: Why You Need Zinc and Where to Find It. but is for informational and educational purposes alone. It comes from the bark of a European pine tree. In another study, Pycnogenol increased glutathione levels and total antioxidants after a month in children with ADHD [42, 43]. Pine bark extract may be the perfect treatment since its an antioxidant dynamo. Are there any risks to taking it? According to a meta-analysis of 9 trials including 549 people, 150-200 mg/day for at least 12 weeks may reduce both diastolic and systolic blood pressure [36]. 3. For improving exercise capacity in athletes: 200 milligrams daily. However, this was a relatively small study, so larger ones are needed to fully understand pine bark extracts role in these findings. DOI: Gulati OP. It decreased concussion symptoms in 42 student-athletes with a history of sports-related concussions after 6 weeks. In a good-quality study, 24 adults aged 24 to 53 years old with attention deficit hyperactivity disorder (ADHD) were given Pycnogenol, placebo, or the standard drug for three weeks. Pycnogenol is a patented extract of the French maritime pine bark (Pinus pinaster). It is found primarily in southwestern France and is used to help people with asthma, allergies, hay fever, and other health conditions.. The researchers concluded that pine bark extract may increase production of hyaluronic acid and collagen, which are both found in many popular antiaging products. Take Helpful Supplements. Studies have found that when taken along with an inhaler, Pycnogenol can reduce leukotrienes, helping to relieve lung inflammation and limit frequency of inhaler use., Many people develop osteoarthritis as they age. By clicking Subscribe, I agree to the WebMD, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Bird Flu Deaths Prompt U.S. to Test Vaccine in Poultry, COVID Treatment in Development Appears Promising, Marriage May Help Keep Your Blood Sugar in Check, Getting Outdoors Might Help You Take Fewer Meds, New Book: Take Control of Your Heart Disease Risk, MINOCA: The Heart Attack You Didnt See Coming, Health News and Information, Delivered to Your Inbox, Becoming a Vegetarian: Foods to Choose From. In some people lung inflammation is caused by leukotrienes chemicals that are released by the body after a person encounters allergens. Pycnogenol-treated patients reported significant improvement with knee pain, as compared to the placebo group. A 2004 animal study also found that applying a gel containing pine bark extract sped up the wound-healing process. Higher doses (200 mg/day) may improve blood vessel health and function after 8 weeks according to a study of 23 people with heart disease [38]. Pycnogenol pine bark extracts contain a unique blend of flavonoids whose antioxidant action is over is 50 times more powerful than vitamin E, 20 times more powerful than vitamin C and 16 times more active than grapeseed extracts. Tongkat ali is an herbal remedy suggested to treat various ailments, including low testosterone and male infertility. In another trial, 30 people with type 2 diabetes received a range of pycnogenol doses. Sort By. The crew fell extremely ill from scurvy, an extreme lack of vitamin C. Cartiers crew crossed paths with a Quebec Indian who encouraged them to drink a tea made from pine bark and needles. During week, five without, treatment, reduction of cramps was maintained in all three groups. Purity and potency of Pycnogenolare continuously monitored . A small 2017 study examined the effects of pine bark extract in treating cardiovascular risk factors associated with menopause. Various brands of pycnogenol are available. In one clinical trial of 156 osteoarthritis patients, pycnogenol reduced pain, stiffness, swelling, and improved joint function after 3 months. are clickable links to these studies. For asthma in children: 1 milligram per pound of body weight given in two divided doses. 3. Beta 1-3D Glucan is recognized by cells in the immune system, and can modify your immune system responses. Subjects in the study that took Pycnogenol ended up taking fewer painkillers [51]. A randomized, double-blind, placebo-controlled study of 60 patients aged six to 18 years old, was conducted over three months during which patients were randomly assigned to receive either Pycnogenol or placebo. Natural Factors Pycnogenol 25mg 60 Veggie Caps. So it may not be safe for people with immune disorders, such as: It's not known if pycnogenol is safe for children or for women who are pregnant or breastfeeding. Pycnogenol and Pine Bark Extract Supplements. Pycnogenol French maritime pine bark extract acts as a potent blend of antioxidants, it is a natural anti-inflammatory, stimulates generation of collagen and hyaluronic acid and help with natural dilation of blood vessels by supporting production of nitric oxide. Rating: 100%. Staves Off Infections. Two studies illustrate the possibilities: One was a randomized, double-blind, placebo-controlled, crossover study in which 26 asthmatic patients were given either a maximum of 200 mg a day of Pycnogenol or placebo for the first period of four weeks and then crossed over to the alternate treatment for the next four weeks. In the study, women taking Pycnogenol were more satisfied and compliant to the regimen [24]. Used early on, it may prevent eye damage and blindness from diabetes [34]. Some people seek to manage ADHD symptoms through an ADHD diet. ( 4) Thus, this powerful extract works as a natural ear infection remedy while improving balance and preventing hearing loss. Our goal is to not have a single piece of inaccurate information on this website. Side effects. Pycnogenol seems well-tolerated for use in adults for up to 6 months. We do not aim to diagnose, treat, cure or prevent any illness or disease. Top 9 Natural Allergy Relief Home Remedies - Dr. Axe 1 week ago from draxe.com Eat an Anti-Inflammatory, Alkaline Diet. All of our content is written by scientists and people with a strong science background. The goal of one study was to evaluate whether or not Pycnogenol could prevent edema (fluid build-up) during long-haul flights in healthy people. Although these may still be high quality, the active compounds are more likely to vary. According to researchers, it may help prevent the rise in free radicals typically seen after exercise, which could cause muscle fatigue and damage [9]. Last medically reviewed on January 24, 2018. Pycnogenol-treated subjects experienced an improvement in all menopausal symptoms. DOI: Luzzi R, et al. Tell your doctor about any supplements you're taking, even if they're natural. But did you know that pine bark extract, like pine oil, is one of natures super antioxidants? Pycnogenol (200 mg/day) may reduce muscle cramps and pain according to a study of 66 healthy people, athletes, and those with venous problems after 4 weeks. For diseases of the retina, including those related to diabetes: 50 milligrams three times daily. New research shows . The list goes on a bit further, as the OPCs in thisextract may inhibit lipid peroxidation, platelet aggregation, capillary permeability and fragility, and to affect enzyme systems, which basically means it may be a natural treatment for many serious health conditions, such as stroke and heart disease. Pycnogenol (pic-noj-en-all) is a natural plant extract originating from the bark of the maritime pine that grows along the coast of southwest France and is found to contain a unique combination of procyanidins, bioflavonoids and phenolic acids, which offer extensive natural health benefits. Vinpocetine is used to increase brain circulation, alertness, cognitive function, concentration, and memory, as well as to lower inflammation and oxidative stress.This article will explore vinpocetine's history, how it works, its potential benefits, and any possible safety issues . Set Ascending Direction. The dosage in most clinical studies varied between 50-360 mg/day. A study of 30 women found that Pycnogenol (75 mg/day) may reduce the skin area affected by melasma as well as lower symptoms of fatigue, constipation, body pain, and anxiety [62]. Studies have been conducted to review the effects of pine bark extract on pseudomonas infectious wounds. It also slightly decreased blood pressure and increased testosterone [67]. Results failed to show any efficacy of Pycnogenol or methylphenidate when compared to placebo. ", Mayo Clinic: High blood pressure (hypertension)., Panminerva Medica: "Pycnogenol improvements in asthma management. While pine bark extract is thought to be safe for children, they should only take it for a few weeks at a time. They were treated with 200 mg of Pycnogenol daily or with placebo. Disclaimer: Results are not guaranteed*** and may vary from person to person***. Pycnogenol is a substance taken from the pine bark of trees found in the southwest region of France. These wounds occur most frequently in hospitals or in those with weakened immune systems, such as after surgery. Study participants took pine bark extract as a supplement, and it was found to be most effective in women who started out with dry skin. . Pycnogenol can help control blood pressure, which helps improve overall heart health. Depending on the extraction process and the source Pinus species used (P. radiata or P. pinaster), the exact composition will vary. Pycnogenol is thought to be an antioxidant that helps protect cells from damage. Regardless of what youre using it for, its best to start with the lowest possible dose. Pycnogenol is considered possibly safe when taken orally or when applied topically as a cream or ointment. There are also several other natural ADHD remedies you can try. DOI: Dvorkov M, et al. After stopping Pycnogenol for one month, symptoms Because of its anti-inflammatory effects, nattokinase has been used to help with pain from arthritis, including that of rheumatoid arthritis. which enables users to obtain detailed information and reports based on their genome. As a skin powder, however, you can use it safely for up to six weeks. A 2006 study found that children who took a daily pine bark extract supplement for four weeks had significantly lower levels of hyperactivity. Pycnogenol is not approved by the FDA for medical use. Eye health. Pycnogenol may stimulate the immune system. Pycnogenol is officially extracted from the French maritime pine (Pinus pinaster), which grows in the southwest coast of France. The study participants symptoms started to return a month after they stopped taking pine bark extract. Moreover, Pycnogenol treatment reduced the use of painkillers. The specific tree from which the bark is extracted is called a maritime pine. Pycnogenol (100 mg/day) supplementation may decrease symptoms of the common cold and speed up recovery, according to a clinical trial of 146 people. Research indicates that Pycnogenol provides an increase in survival performance of train athletes. Pycnogenol reduced foot swelling in 79% of the patients, versus one percent in the placebo group. Pycnogenol has not been found to cause these issues however, it may take a little longer the feel the relief from pain than aspirin. DOI: Scheff SW, et al. Due to its anti-inflammatory properties, luteolin is being researched as a potential complementary treatment for multiple . You should also avoid using pine bark extract without talking to your doctor first if you: You should also do additional research or talk to your doctor before taking pine bark extract if you also take: While pine bark extract is a natural supplement, it can have powerful effects on your health, both positive and negative. 1. Its used as a natural supplement for several conditions, including dry skin and ADHD. The information in our articles is NOT intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice. Pycnogenol effects on skin elasticity and hydration coincide with increased gene expressions of collagen type I and hyaluronic acid synthase in women [Abstract]. Eighty-six patients were treated either with Pycnogenol at 150 mg or 300 mg daily or the drugs diosmin and hesperidin (Daflon)at 1,000 mg daily for two months. Lower the risk of Alzheimer's disease. 7. Pycnogenol is the registered trademark name for a French formula. In a study of 100 healthy women mostly in their early 40s with mild sexual dysfunction, a combination product with Pycnogenol (Lady Prelox) improved sexual function over 8 weeks [74]. Proper nutrition is essential for ADHD treatment. Another study in 2012 showed that Pycnogenol alone, at a dose of 75 mg/day, increased skin hydration by 8% after just 6 weeks; in women with dry skin at baseline the increase was 21%. Diarrhea. Here are some basic guidelines as reported by WebMD: While most studies do not indicate major side effects, pine bark extract may cause irritability and fatigue, and could interact with other drugs. The studies revealed that the sperm concentration greatly increased after about eight to 16 weeks of treatment, to include improved orgasmic function. chronic anal fissure may take more than 6 weeks to heal. In a good-quality study, 77 patients with osteoarthritis were treated with 100 mg of Pycnogenol daily and 79 patients were treated with placebo for three months. A study of 32 people with heart failure lasting 12 weeks suggests that a combination of Pycnogenol with CoQ10 (PycnoQ10) may improve blood pressure, heart function, edema, and capacity for physical activity [40]. 2. Not bad. Interactions. In a smaller study of 58 people, pycnogenol reduced the inflammatory marker CRP [49, 50]. Pycnogenol (100 mg/day) may reduce leg swelling, spider veins, and cramps according to a study of 133 women with varicose veins who recently gave birth. Pycnogenol suppresses inflammation and regulates the production of nitric oxide - a . Plus, it reduced total and LDL (bad) cholesterol. Some people who have asthma have higher levels of leukotrienes in their blood. Pine bark extract can help reduce muscle soreness and may help improve conditions relating to poor circulation, high blood pressure, osteoarthritis, diabetes, ADHD, female reproductive issues, skin, erectile dysfunction, eye disease and sports stamina. ", Natural Medicines Comprehensive Database web site: "Pycnogenol.". 1. Our science team is put through the strictest vetting process in the health industry and we often reject applicants who have written articles for many of the largest health websites that are deemed trustworthy. It can also stabilize mast cells, which release histamine and trigger allergic reactions. (13). Pycnogenol accelerates wound healing and reduces scar formation [Abstract]. However, research on these two groups is limited [71, 15]. 2005-2023 Healthline Media a Red Ventures Company. Another clinical trial of 76 people with allergic asthma also suggests that Pycnogenol may reduce IgE antibodies and asthma symptoms [18, 16]. This plant extract also shows promise in such far-flung conditions as traumatic brain injury 40,41, skin problems 37, pain syndromes 38,39, and even tinnitus . There were 88 in the control group and 81 in the Pycnogenol group. (11, 12), While both eliminate pain, the pine bark extract is a far better choice. More research is needed to see how this supplement affects all of these conditions. Some risks associated with Pycnogenol include:, Pycnogenol and other maritime tree barks have not been studied as extensively as traditional medicine. A study of 147 people found that pycnogenol (100 mg/day) may improve running, push-ups, and sit-ups endurance in recreational athletes over an 8-week training program. Another study found this supplement can even halt progression of vision . Risks. Pycnogenol (up to 200 mg/day) may improve asthma and reduce inflammatory asthma markers in the blood, leukotrienes, after 4 weeks, according to a randomized placebo-controlled trial of 26 asthma patients [14]. There is a seemingly growing problem with skin exposure to ultraviolet radiation and the confusion of how to get vitamin D from the sun while avoiding these skin-damaging rays. A high number signals high blood pressure. High levels of both of these are considered risk factors for heart disease. Taking pycnogenol daily for 2 months seems to slow or prevent further worsening of retinal disease caused by diabetes, atherosclerosis, or other diseases. All included participants had subclinical cognitive impairment, which looks like typical brain fog [22]. Once youre sure that you dont have any negative reactions, you may be able to increase your dosage according to the label. But two months ago, erectile dysfunction health food with the help of the Divine Tool Alliance, the price of all materials related to the puppet mechanism was raised by 20 erectile dysfunction health food 30 , and the price of selling the puppet was reduced by 10. In a study of 77 people with symptoms of Irritable Bowel Syndrome (IBS), Pycnogenol (150 mg/day) improved symptoms and reduced the frequency of attacks [77]. The study provided clear evidence that Pycnogenol does, indeed, offer photoprotection however, it came out even better than expected, showing that it may be used to reduce hyperpigmentation of human skin while improving the skin barrier function and extracellular matrix homeostasis. (6). Circulation and Jet Lag on Long Flights. Rakel, D. Integrative Medicine, 3rd edition, Saunders, 2012. A study of 66 healthy adults found that Pycnogenol may reduce the number of leg cramps experienced [11]. If youre native to Oregon, you likely know all about marionberries. However, it's always a good idea to start with a low dose so you can monitor how your body responds.